The broad array of scientific pursuits in the early modern period was inseparable from the development of spaces for the conceptualization, synthesis, and production of knowledge. New technology was tested in courts, nature was replicated in the workshop, and public dissections began to be conducted in universities. How did such spaces delineate new understandings of science through the formalization of practice or the privileging of observation? How did they contribute to the formulation and transmission of scientific knowledge? This course takes as its subject the emergence of these kinds of spaces, considering the library, the laboratory, the botanical garden, the anatomy theater, the observatory, the workshop, the utopian space, and the space of the unknown. Essays by Katharine Park, Lorraine Daston, Antoine Picon, Paula Findlen, Peter Galison, Pamela Smith, Anthony Grafton, Steven Shapin and others will be paired with theoretical texts including Latour, Bachelard, Simmel, and Lefebvre. Primary sources by Vesalius, Cellini, Johannes Kepler, Thomas More, Samuel Quiccheberg, Tycho Brahe, and Leonhart Fuchs.